Volume of distribution (Vd) is a pharmacokinetic measurement that describes the distribution of a drug throughout the body's fluids and tissues. It helps to understand how extensively a drug disperses from the bloodstream into body compartments, which is crucial for determining appropriate dosing and understanding drug behavior in the body. A higher volume of distribution indicates that the drug is extensively distributed in tissues outside the plasma, whereas a lower volume suggests it remains primarily in the blood circulation.
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