Volume of distribution (Vd) is a pharmacological term that describes the extent to which a drug disperses throughout the body's fluids and tissues relative to the concentration of the drug in the blood plasma. This concept is crucial in understanding how a drug behaves in the body, influencing both its therapeutic effectiveness and potential toxicity. A high volume of distribution indicates that a drug extensively distributes into tissues, whereas a low volume suggests that it remains largely in the bloodstream.
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