Risedronate

Definition

Risedronate is a bisphosphonate medication used to treat and prevent osteoporosis by inhibiting bone resorption. It works by binding to hydroxyapatite found in bone, which slows down the activity of osteoclasts.

5 Must Know Facts For Your Next Test

1. Risedronate is commonly prescribed for postmenopausal women to reduce the risk of fractures.
2. Patients should take Risedronate with a full glass of water and remain upright for at least 30 minutes afterward to avoid gastrointestinal irritation.
3. The medication should be taken on an empty stomach, at least 30 minutes before any food, beverage, or other medications.
4. Common side effects include gastrointestinal issues such as abdominal pain, dyspepsia, and esophagitis.
5. Risedronate may interact with calcium supplements or antacids if taken simultaneously; they should be taken at different times.

Review Questions

• What is the primary mechanism of action for Risedronate?
• Why must patients remain upright after taking Risedronate?
• What are some common side effects associated with Risedronate?

Related terms

Alendronate:

Another bisphosphonate used to treat osteoporosis by inhibiting osteoclast-mediated bone resorption.

Calcitriol:

A form of Vitamin D used to manage low calcium levels in the blood and promote bone health.

Raloxifene:

An estrogen receptor modulator that mimics estrogen's favorable effects on bone density without some of its risks.