Raloxifene

Definition

Raloxifene is a selective estrogen receptor modulator (SERM) used primarily to treat and prevent osteoporosis in postmenopausal women. It also reduces the risk of invasive breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer.

5 Must Know Facts For Your Next Test

1. Raloxifene mimics estrogen's beneficial effects on bone density while blocking its potentially harmful effects on breast and uterine tissues.
2. It is administered orally, typically at a dose of 60 mg once daily.
3. Common side effects include hot flashes, leg cramps, and an increased risk of blood clots.
4. Raloxifene does not treat menopausal symptoms such as hot flashes; rather, it may actually cause them.
5. Contraindications include a history of venous thromboembolism and pregnancy.

Review Questions

• What are the primary uses of raloxifene in postmenopausal women?
• What are some common side effects associated with raloxifene?
• Why might raloxifene be contraindicated for certain patients?

Related terms

Bisphosphonates:

A class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases.

Calcium Preparations:

Supplements that provide calcium to help maintain bone health and prevent osteoporosis.

Vitamin D:

A fat-soluble vitamin crucial for maintaining bone health by aiding calcium absorption.