Amoxicillin-clavulanate

Definition

Amoxicillin-clavulanate is a combination antibiotic containing amoxicillin, a penicillin derivative, and clavulanate potassium, a beta-lactamase inhibitor. It is used to treat various bacterial infections by enhancing the effectiveness of amoxicillin against resistant bacteria.

5 Must Know Facts For Your Next Test

1. Amoxicillin-clavulanate is effective against both Gram-positive and Gram-negative bacteria.
2. Clavulanate potassium inhibits beta-lactamase enzymes produced by resistant bacteria, allowing amoxicillin to work effectively.
3. Commonly prescribed for infections such as sinusitis, otitis media, and respiratory tract infections.
4. Available in various forms including tablets, chewable tablets, and oral suspensions.
5. Side effects may include gastrointestinal upset, allergic reactions, and potential liver enzyme elevation.

Review Questions

• What role does clavulanate play in the effectiveness of amoxicillin-clavulanate?
• List three common infections that amoxicillin-clavulanate is used to treat.
• What are some potential side effects of taking amoxicillin-clavulanate?

Related terms

Penicillin:

A group of antibiotics derived from Penicillium fungi used to treat bacterial infections.

Beta-lactamase Inhibitors: Compounds that block the activity of beta-lactamase enzymes produced by certain bacteria.

Otic Anti-infectives: Medications used to treat ear infections caused by bacteria or other microorganisms.