Sulfamethoxazole-Trimethoprim

Definition

Sulfamethoxazole-Trimethoprim is a combination antibiotic used to treat a variety of bacterial infections. It is particularly effective against gastrointestinal infections and urinary tract infections.

5 Must Know Facts For Your Next Test

1. Sulfamethoxazole-Trimethoprim works by inhibiting bacterial synthesis of dihydrofolic acid.
2. Common side effects include nausea, vomiting, and loss of appetite.
3. Patients with gastrointestinal conditions must be monitored for dehydration due to potential side effects like diarrhea.
4. This combination drug can interfere with folate metabolism, which is crucial for cell division and growth.
5. Sulfamethoxazole-Trimethoprim should be taken with a full glass of water to reduce the risk of crystalluria.

Review Questions

• What are the common side effects of Sulfamethoxazole-Trimethoprim?
• How does Sulfamethoxazole-Trimethoprim affect folate metabolism?
• Why is it important to monitor hydration levels in patients taking Sulfamethoxazole-Trimethoprim?

Related terms

Dihydrofolic Acid: A form of folic acid that bacteria need to multiply and grow.

Crystalluria: The presence of crystals in the urine, which can occur when certain medications are not taken with enough water.

Dehydration: A condition resulting from excessive loss of body water, often exacerbated by gastrointestinal issues or certain medications.