Entecavir

Definition

Entecavir is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection. It works by inhibiting the replication of the virus, thereby reducing viral load in the liver.

5 Must Know Facts For Your Next Test

1. Entecavir is a nucleoside analogue that specifically targets HBV DNA polymerase.
2. It is typically prescribed for patients with evidence of active viral replication and liver inflammation.
3. Resistance to entecavir can develop, particularly in patients who have been previously treated with other nucleoside analogues.
4. Common side effects include headache, fatigue, dizziness, and nausea.
5. Regular monitoring of liver function and viral load is essential during entecavir therapy.

Review Questions

• What is the primary mechanism of action of entecavir?
• What are some common side effects associated with entecavir?
• Why is regular monitoring important during entecavir treatment?

Related terms

Hepatitis B Virus (HBV): A virus that infects the liver and can cause both acute and chronic disease.

Nucleoside Analogue: A class of antiviral drugs that mimic natural nucleosides to inhibit viral replication.

Liver Function Tests (LFTs): Blood tests used to assess the health and function of the liver.