Voltage-gated sodium channels

Definition

Voltage-gated sodium channels are specialized protein structures in the membrane of skeletal muscle cells that open in response to changes in membrane potential, allowing sodium ions (Na+) to flow into the cell. This influx of Na+ is crucial for initiating muscle contraction.

Related terms

Action potential: A rapid rise and fall in electrical charge across a cell's membrane, which propagates along the length of neurons or muscle fibers.

Membrane potential: The electrical voltage difference across a cell's plasma membrane, which is essential for conducting nerve impulses and initiating muscle contractions.

Muscle contraction: The process by which muscle fibers generate tension through the action of actin and myosin cross-bridges, resulting in shortening or generating force against an object