Physiologically-based pharmacokinetic modeling (PBPK) is a computational method used to predict the absorption, distribution, metabolism, and excretion of chemicals in biological systems by using physiological parameters. This modeling approach integrates data from various sources, including anatomy, physiology, and biochemistry, to create a more realistic simulation of how substances behave in the body. It allows for a better understanding of toxicokinetics and is particularly useful in assessing the potential effects of chemical exposure on human health.
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