Gastrointestinal bleeding refers to any form of bleeding that occurs within the digestive tract, which can range from the mouth to the anus. This condition is significant in clinical practice as it can lead to serious health complications, including shock and death, if not addressed promptly. Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to increase the risk of gastrointestinal bleeding due to their effects on the gastric mucosa and inhibition of prostaglandin synthesis, which is crucial for maintaining the protective lining of the gastrointestinal tract.
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