Vortioxetine

Definition

Vortioxetine is an antidepressant used to treat major depressive disorder (MDD). It functions as a serotonin modulator and stimulator, impacting various serotonin receptors.

5 Must Know Facts For Your Next Test

1. Vortioxetine has a unique mechanism of action, acting as both a serotonin reuptake inhibitor and a direct modulator of various serotonin receptors.
2. Common side effects include nausea, headaches, and dizziness.
3. It is metabolized primarily by the liver enzyme CYP2D6.
4. Vortioxetine may improve cognitive function in patients with depression.
5. The typical starting dose for adults is 10 mg once daily, which can be adjusted based on patient response.

Review Questions

• What is the primary use of Vortioxetine?
• Which enzyme is primarily responsible for the metabolism of Vortioxetine?
• List two common side effects associated with Vortioxetine.

Related terms

Serotonin Reuptake Inhibitor: A class of drugs that block the reabsorption of serotonin into neurons, increasing its availability in the brain.

Major Depressive Disorder (MDD): A mental health condition characterized by persistent feelings of sadness and loss of interest in activities.

CYP2D6: An enzyme that metabolizes approximately 25% of all medications, including many antidepressants like Vortioxetine.