Triptans

Definition

Triptans are a class of medications specifically used to treat acute migraine attacks. They work by stimulating serotonin receptors, leading to the constriction of blood vessels in the brain and reducing inflammation.

5 Must Know Facts For Your Next Test

1. Triptans are most effective when taken at the onset of migraine symptoms.
2. Common side effects include dizziness, drowsiness, and muscle weakness.
3. They should not be used in patients with cardiovascular diseases due to potential vasoconstrictive effects.
4. Sumatriptan was the first triptan approved by the FDA for migraine treatment.
5. Triptans can interact with other serotonergic drugs, increasing the risk of serotonin syndrome.

Review Questions

• What is the primary mechanism of action for triptans in treating migraines?
• Why should triptans be avoided in patients with cardiovascular conditions?
• Name one common side effect associated with triptan use.

Related terms

Serotonin: A neurotransmitter involved in mood regulation and vasoconstriction.

Sumatriptan: The first triptan drug approved for treating acute migraines.

Serotonin Syndrome: A potentially life-threatening condition caused by excessive serotonergic activity.