Triamterene

Definition

Triamterene is a potassium-sparing diuretic that helps prevent your body from absorbing too much salt and keeps your potassium levels from getting too low. It is commonly used in combination with other diuretics to treat fluid retention and high blood pressure.

5 Must Know Facts For Your Next Test

1. Triamterene works by inhibiting sodium reabsorption in the distal convoluted tubule of the kidney.
2. It is often used in combination with thiazide diuretics to counteract potassium loss.
3. Common side effects include hyperkalemia, dizziness, and headache.
4. Patients with severe kidney impairment or hyperkalemia should not use Triamterene.
5. Monitoring of blood electrolyte levels is essential when a patient is on Triamterene.

Review Questions

• What mechanism does Triamterene use to spare potassium?
• Why is Triamterene often combined with thiazide diuretics?
• What are the contraindications for using Triamterene?

Related terms

Thiazide Diuretics: A class of diuretics that inhibit sodium reabsorption in the distal convoluted tubule, leading to increased urine output.

Hyperkalemia: A condition characterized by abnormally high levels of potassium in the blood.

Distal Convoluted Tubule: The portion of the nephron in the kidney where selective reabsorption occurs, targeted by some diuretics like Triamterene.