Tagamet HB

Definition

Tagamet HB is an over-the-counter histamine H2 receptor antagonist used to reduce stomach acid production, primarily for treating conditions like heartburn and ulcers.

5 Must Know Facts For Your Next Test

1. Tagamet HB inhibits the action of histamine at the H2 receptors in the stomach lining, thereby decreasing acid secretion.
2. It is commonly used for conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
3. Typical side effects include headache, dizziness, and gastrointestinal disturbances like diarrhea or constipation.
4. Cimetidine, the active ingredient in Tagamet HB, can interact with other medications by inhibiting cytochrome P450 enzymes.
5. Long-term use of Tagamet HB may lead to vitamin B12 deficiency due to reduced absorption.

Review Questions

• What is the primary mechanism of action for Tagamet HB?
• Which conditions are commonly treated using Tagamet HB?
• What are potential side effects associated with Tagamet HB?

Related terms

Histamine H2 Receptor Antagonist: A class of drugs that block histamine-induced gastric acid secretion.

Proton-Pump Inhibitors (PPIs): Medications that irreversibly inhibit the hydrogen/potassium ATPase enzyme system of gastric parietal cells.

Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach contents flow back into the esophagus causing symptoms like heartburn.