Sucralfate

Definition

Sucralfate is a medication used to treat and prevent ulcers in the intestines. It works by forming a protective barrier on the ulcer site against stomach acid and pepsin.

5 Must Know Facts For Your Next Test

1. Sucralfate is often prescribed for patients with duodenal ulcers.
2. The medication is typically taken on an empty stomach, usually one hour before meals.
3. Sucralfate requires acidic conditions to be activated; hence, it should not be taken with antacids.
4. Common side effects include constipation and dry mouth.
5. It is not absorbed systemically, making it safer for long-term use compared to other ulcer medications.

Review Questions

• What is the primary therapeutic use of Sucralfate?
• Why should Sucralfate be taken on an empty stomach?
• What are common side effects associated with Sucralfate?

Related terms

Pepsin Inhibitors: Medications that decrease gastric secretion and activity of pepsin, an enzyme involved in digestion.

Prostaglandin Analogues: Drugs that mimic the action of prostaglandins, protecting the stomach lining by increasing mucus production.

Antacids: Substances that neutralize stomach acid to relieve heartburn and indigestion.