Soluble guanylate cyclase (sGC) is an enzyme that plays a crucial role in the regulation of cardiovascular function, particularly in the context of heart failure. It acts as a receptor for the signaling molecule nitric oxide (NO), catalyzing the conversion of guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP), which then mediates various physiological responses related to cardiovascular health.
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