Silver sulfadiazine

Definition

Silver sulfadiazine is a topical antimicrobial agent used primarily on burns to prevent and treat infections. It works by inhibiting bacterial growth at the site of application.

5 Must Know Facts For Your Next Test

1. Silver sulfadiazine is effective against a wide range of Gram-positive and Gram-negative bacteria, as well as some fungi.
2. It should be applied to the burn area once or twice daily using sterile gloved hands.
3. Common side effects include itching, rash, and a burning sensation at the application site.
4. Contraindications for its use include patients with sulfa allergies and pregnant women near term due to potential risks to the fetus.
5. It is important to monitor for signs of systemic absorption, particularly in patients with extensive burns.

Review Questions

• What types of microorganisms does silver sulfadiazine target?
• How should silver sulfadiazine be applied to a burn wound?
• What are some common side effects associated with the use of silver sulfadiazine?

Related terms

Mafenide Acetate: Another topical antimicrobial used for treating burns, effective against both bacteria and some fungi.

Bacitracin: An antibiotic ointment commonly used in minor skin infections and small burns.

Topical Antiseptics: Substances applied to living tissue/skin to reduce the possibility of infection, sepsis, or putrefaction.