Selective serotonin receptor agonists

Definition

Selective serotonin receptor agonists are drugs that specifically target and activate serotonin receptors in the brain to alleviate migraine headaches. They primarily work by narrowing blood vessels and reducing inflammation.

5 Must Know Facts For Your Next Test

1. Selective serotonin receptor agonists are commonly known as triptans.
2. They are most effective when taken at the first sign of a migraine headache.
3. Common side effects include dizziness, fatigue, and tingling sensations.
4. These drugs should not be used by individuals with cardiovascular diseases due to potential vasoconstriction.
5. Sumatriptan was the first selective serotonin receptor agonist approved for treating migraines.

Review Questions

• What is the primary mechanism of action for selective serotonin receptor agonists in treating migraines?
• Why are selective serotonin receptor agonists contraindicated in patients with cardiovascular diseases?
• What is a common side effect associated with the use of triptans?

Related terms

Serotonin: A neurotransmitter involved in mood regulation and pain perception.

Migraine Headache: A type of headache characterized by severe pain, often accompanied by nausea and sensitivity to light or sound.

Vasoconstriction: The narrowing of blood vessels resulting from contraction of the muscular wall of the vessels.