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Rizatriptan

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Pharmacology for Nurses

Definition

Rizatriptan is a selective serotonin receptor agonist used to treat acute migraine headaches. It works by narrowing blood vessels around the brain and reducing substances in the body that trigger migraine pain, nausea, and sensitivity to light and sound.

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5 Must Know Facts For Your Next Test

  1. Rizatriptan is typically administered orally in the form of tablets or orally disintegrating tablets.
  2. It is most effective when taken at the first sign of a migraine headache.
  3. Rizatriptan should not be used as a preventive treatment for migraines or for treating cluster headaches.
  4. Common side effects include dizziness, drowsiness, and fatigue; serious side effects may include chest pain or tightness.
  5. Patients with cardiovascular conditions such as ischemic heart disease should avoid using rizatriptan due to its vasoconstrictive properties.

Review Questions

  • What is the primary mechanism of action for rizatriptan?
  • When should rizatriptan be administered for maximum effectiveness?
  • What are some common side effects associated with rizatriptan use?

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