Reversible Acetylcholinesterase Inhibitors
from class:
Pharmacology for Nurses
Definition
Reversible acetylcholinesterase inhibitors are drugs that temporarily inhibit the enzyme acetylcholinesterase, leading to increased levels of acetylcholine at synaptic junctions. They are used in the management of conditions like myasthenia gravis and Alzheimer's disease.
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5 Must Know Facts For Your Next Test
- These inhibitors prevent the breakdown of acetylcholine, enhancing cholinergic transmission.
- Common examples include neostigmine, pyridostigmine, and donepezil.
- They are crucial in treating myasthenia gravis by improving muscle strength.
- In Alzheimer's disease, they help alleviate symptoms by boosting cognitive function.
- Side effects may include bradycardia, gastrointestinal distress, and increased salivation.
Review Questions
- What is the primary mechanism of action for reversible acetylcholinesterase inhibitors?
- Name two conditions that can be treated with reversible acetylcholinesterase inhibitors.
- List one common side effect associated with these inhibitors.
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