Prilosec

Definition

Prilosec is a brand name for omeprazole, a proton-pump inhibitor used to treat gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid. It works by reducing the amount of acid produced in the stomach.

5 Must Know Facts For Your Next Test

1. Prilosec is commonly prescribed for conditions like GERD, Zollinger-Ellison syndrome, and peptic ulcers.
2. Omeprazole, the active ingredient in Prilosec, inhibits the hydrogen-potassium ATPase enzyme system of gastric parietal cells.
3. It is typically taken once daily before meals for optimal effectiveness.
4. Long-term use of Prilosec can lead to potential side effects such as vitamin B12 deficiency and an increased risk of bone fractures.
5. Prilosec may interact with certain medications such as clopidogrel, reducing its effectiveness.

Review Questions

• What is the primary mechanism of action for Prilosec?
• Name two medical conditions that Prilosec is commonly prescribed to treat.
• What are some potential long-term side effects of using Prilosec?

Related terms

Proton-Pump Inhibitors (PPIs): A class of drugs that reduce stomach acid production by blocking the hydrogen-potassium ATPase enzyme system.

Histamine H2-Receptor Antagonists: Medications that reduce stomach acid by blocking histamine on parietal cells in the stomach lining.

Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid frequently flows back into the esophagus, causing irritation.