Pravachol
from class:
Pharmacology for Nurses
Definition
Pravachol is a brand name for pravastatin, a statin medication that lowers cholesterol levels by inhibiting HMG-CoA reductase. It is used to reduce the risk of cardiovascular disease and manage hyperlipidemia.
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5 Must Know Facts For Your Next Test
- Pravachol works by inhibiting the enzyme HMG-CoA reductase, which is crucial in the cholesterol synthesis pathway.
- It is primarily used to lower LDL cholesterol and triglycerides while modestly increasing HDL cholesterol.
- Adverse effects may include muscle pain, liver dysfunction, and increased blood sugar levels.
- Pravachol is metabolized differently compared to other statins, primarily through sulfation rather than cytochrome P450 enzymes.
- It can be taken with or without food but should be taken at the same time each day for consistent effectiveness.
Review Questions
- What enzyme does Pravachol inhibit to lower cholesterol levels?
- List three common adverse effects associated with Pravachol.
- How does Pravachol's metabolism differ from other statins?
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