Plaques

Definition

Plaques are abnormal accumulations of protein or other substances that form in tissues and organs. In the context of multiple sclerosis, plaques are areas of damaged myelin in the central nervous system.

5 Must Know Facts For Your Next Test

1. In multiple sclerosis, plaques are visible on MRI scans as lesions.
2. Plaques cause disruption in nerve signal transmission leading to neurological symptoms.
3. The formation of plaques is associated with autoimmune activity against myelin.
4. Management of multiple sclerosis often involves drugs aimed at reducing plaque formation and inflammation.
5. In dermatologic disorders like psoriasis, plaques refer to raised, red patches covered with a silvery white buildup of dead skin cells.

Review Questions

• What role do plaques play in the pathology of multiple sclerosis?
• How do plaques affect nerve signal transmission in multiple sclerosis?
• What is the difference between plaques in multiple sclerosis and those seen in psoriatic conditions?

Related terms

Myelin: A fatty substance that surrounds nerve fibers and helps increase the speed of electrical communication between neurons.

Autoimmune Disease: A condition where the immune system mistakenly attacks the body's own tissues.

Psoriasis: A chronic skin disorder characterized by red, scaly patches called plaques.