Piroxicam

Definition

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as arthritis. It works by inhibiting the enzymes that produce prostaglandins, compounds involved in inflammation.

5 Must Know Facts For Your Next Test

1. Piroxicam inhibits cyclooxygenase (COX) enzymes, reducing the formation of pro-inflammatory prostaglandins.
2. It is commonly prescribed for conditions like osteoarthritis and rheumatoid arthritis.
3. Piroxicam has a long half-life, allowing for once-daily dosing.
4. Common side effects include gastrointestinal issues such as ulcers and bleeding.
5. It should be used with caution in patients with cardiovascular risk factors due to potential increased risk of heart attack or stroke.

Review Questions

• What enzymes does Piroxicam inhibit to reduce inflammation?
• For which types of arthritis is Piroxicam commonly prescribed?
• Why should Piroxicam be used cautiously in patients with cardiovascular risks?

Related terms

NSAID: Nonsteroidal anti-inflammatory drugs that reduce pain and inflammation by inhibiting COX enzymes.

Prostaglandins: Compounds involved in the inflammatory response, pain, and fever.

Cyclooxygenase (COX): Enzymes responsible for the formation of prostaglandins from arachidonic acid.