Pantoprazole

Definition

Pantoprazole is a proton-pump inhibitor (PPI) used to reduce stomach acid production. It is commonly prescribed for conditions such as gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome.

5 Must Know Facts For Your Next Test

1. Pantoprazole works by inhibiting the hydrogen/potassium ATPase enzyme system at the surface of gastric parietal cells.
2. It is typically administered orally, but can also be given intravenously in hospital settings.
3. Common side effects include headache, diarrhea, nausea, and abdominal pain.
4. Pantoprazole should not be taken with certain drugs like atazanavir due to potential drug interactions.
5. It is generally prescribed for short-term treatment, often ranging from four to eight weeks.

Review Questions

• What mechanism does pantoprazole use to reduce stomach acid?
• List two common side effects of pantoprazole.
• Why should pantoprazole not be taken with atazanavir?

Related terms

Omeprazole: Another proton-pump inhibitor used to treat similar conditions as pantoprazole.

Histamine Blockers: Drugs that reduce stomach acid by blocking histamine receptors on parietal cells.

Proton-Pump Inhibitors (PPIs): A class of drugs that reduce stomach acid production by inhibiting the hydrogen/potassium ATPase enzyme system in gastric parietal cells.