Oxicams

Definition

Oxicams are a class of nonsteroidal anti-inflammatory drugs (NSAIDs) that help reduce inflammation and pain. They work by inhibiting the enzyme cyclooxygenase, which decreases the production of prostaglandins involved in inflammation.

5 Must Know Facts For Your Next Test

1. Oxicams are commonly used to treat conditions like rheumatoid arthritis and osteoarthritis.
2. The most well-known oxicam is piroxicam, but others include meloxicam and lornoxicam.
3. Oxicams have a long half-life, allowing for once-daily dosing in many cases.
4. They can cause gastrointestinal side effects such as ulcers and bleeding, similar to other NSAIDs.
5. Oxicams should be used cautiously in patients with renal impairment or cardiovascular issues.

Review Questions

• What is the mechanism of action for oxicams?
• Name two conditions that oxicams are typically prescribed for.
• What are some common side effects associated with oxicam use?

Related terms

NSAIDs: Nonsteroidal anti-inflammatory drugs used to reduce pain and inflammation.

Cyclooxygenase (COX): An enzyme targeted by NSAIDs to reduce the production of inflammatory prostaglandins.

Prostaglandins: Lipid compounds that play a key role in inflammation and pain signaling.