Nystatin

Definition

Nystatin is an antifungal medication used to treat fungal infections, particularly those caused by Candida species. It is commonly available in oral and topical formulations.

5 Must Know Facts For Your Next Test

1. Nystatin works by binding to ergosterol in the fungal cell membrane, causing cell leakage and death.
2. It is often prescribed for oral thrush, a common Candida infection in the mouth.
3. Nystatin is not absorbed into the bloodstream when taken orally, making it safe for treating localized infections.
4. Topical formulations of Nystatin are used for cutaneous or mucocutaneous fungal infections.
5. Common side effects include nausea, vomiting, diarrhea, and skin irritation.

Review Questions

• What mechanism does Nystatin use to exert its antifungal effects?
• For which type of infections is oral Nystatin commonly prescribed?
• Why is Nystatin considered safe for localized treatment?

Related terms

Amphotericin B: An antifungal drug that also binds to ergosterol in fungal cell membranes but can be used systemically.

Fluconazole: An antifungal medication that inhibits ergosterol synthesis and can treat systemic infections.

Candida: A genus of yeast-like fungi that frequently causes opportunistic infections, particularly in immunocompromised individuals.