Norethindrone acetate

Definition

Norethindrone acetate is a synthetic progestin used in various hormonal contraceptives and hormone replacement therapies. It mimics the effects of natural progesterone to regulate menstrual cycles and prevent pregnancy.

5 Must Know Facts For Your Next Test

1. Norethindrone acetate is commonly used in combination oral contraceptive pills.
2. It works by inhibiting ovulation, thickening cervical mucus, and altering the endometrial lining.
3. It can be used to treat conditions like endometriosis and abnormal uterine bleeding.
4. Common side effects include nausea, breast tenderness, and menstrual irregularities.
5. Contraindications include a history of thromboembolic disorders, liver disease, and known or suspected pregnancy.

Review Questions

• What are the primary mechanisms of action for norethindrone acetate in contraception?
• List three common side effects associated with norethindrone acetate.
• Why is norethindrone acetate contraindicated in individuals with a history of thromboembolic disorders?

Related terms

Ethinyl Estradiol: A synthetic estrogen commonly combined with progestins like norethindrone acetate in oral contraceptives.

Levonorgestrel: Another synthetic progestin used in various forms of hormonal contraception including IUDs and emergency contraception pills.

Progesterone: A natural hormone involved in the menstrual cycle and pregnancy, often mimicked by synthetic progestins like norethindrone acetate.