Nizatidine

Definition

Nizatidine is a histamine H2 receptor antagonist used to reduce stomach acid production. It is commonly prescribed for the treatment of ulcers and gastroesophageal reflux disease (GERD).

5 Must Know Facts For Your Next Test

1. Nizatidine works by blocking histamine H2 receptors in the stomach lining, thereby reducing gastric acid secretion.
2. It is effective in treating both duodenal and gastric ulcers.
3. Common side effects include headache, dizziness, and gastrointestinal disturbances such as nausea or diarrhea.
4. Nizatidine is usually administered orally in capsule form, typically at bedtime or before meals.
5. Patients with renal impairment may require dosage adjustments due to decreased clearance of the drug.

Review Questions

• How does Nizatidine reduce stomach acid production?
• What are some common side effects associated with Nizatidine?
• Why might dosage adjustments be necessary for patients with renal impairment when taking Nizatidine?

Related terms

Ranitidine: Another H2 receptor antagonist used to decrease stomach acid production.

Omeprazole: A proton-pump inhibitor that reduces gastric acid secretion by inhibiting the enzyme H+/K+ ATPase.

Gastroesophageal Reflux Disease (GERD): A chronic condition where stomach acid frequently flows back into the esophagus, causing irritation.