Nicotine receptor agonist

Definition

A nicotine receptor agonist is a substance that mimics the action of nicotine by binding to and activating nicotinic acetylcholine receptors in the brain, leading to effects such as increased dopamine release. These drugs are often used in smoking cessation therapies.

5 Must Know Facts For Your Next Test

1. Nicotine receptor agonists can help reduce withdrawal symptoms during smoking cessation.
2. Varenicline is a commonly prescribed nicotine receptor agonist.
3. These agonists work by partially stimulating nicotinic receptors while blocking nicotine from binding to them.
4. Side effects can include nausea, insomnia, and vivid dreams.
5. Nicotine receptor agonists are usually part of a comprehensive treatment plan that includes behavioral therapy.

Review Questions

• What is the primary mechanism of action for a nicotine receptor agonist?
• Name a common drug that acts as a nicotine receptor agonist used in smoking cessation therapy.
• List three potential side effects of nicotine receptor agonists.

Related terms

Nicotinic Acetylcholine Receptor: A type of receptor in the brain that responds to nicotine and acetylcholine.

Varenicline: A medication used to treat nicotine addiction by acting as a partial agonist at nicotinic receptors.

Smoking Cessation: The process of discontinuing tobacco smoking, often involving behavioral support and medications.