Nexterone

Definition

Nexterone is a brand name for amiodarone used to treat and prevent various types of serious, life-threatening ventricular arrhythmias. It works by blocking potassium channels in the heart, prolonging the action potential and refractory period.

5 Must Know Facts For Your Next Test

1. Nexterone is primarily used for managing ventricular tachycardia and ventricular fibrillation.
2. It extends the action potential duration and refractory period by inhibiting potassium channels.
3. Nexterone can be administered intravenously in acute settings and orally for long-term management.
4. Common side effects include hypotension, bradycardia, and potential thyroid or liver dysfunction due to its iodine content.
5. Patients on Nexterone require regular monitoring of liver function tests, thyroid function tests, and pulmonary function.

Review Questions

• What type of arrhythmias is Nexterone primarily used to treat?
• How does Nexterone affect the action potential duration and refractory period?
• What are some common side effects associated with Nexterone?

Related terms

Amiodarone: A medication used to treat various types of cardiac dysrhythmias by blocking potassium channels.

Ventricular Tachycardia: A type of fast heart rate that arises from improper electrical activity in the ventricles of the heart.

Potassium Channel Blockers: A class of drugs that work by inhibiting potassium channels, thus prolonging repolarization in cardiac cells.