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Multaq

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Pharmacology for Nurses

Definition

Multaq (dronedarone) is a Class III antiarrhythmic medication used to manage atrial fibrillation and atrial flutter by blocking potassium channels. It helps maintain normal heart rhythm in patients with these conditions.

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5 Must Know Facts For Your Next Test

  1. Multaq works by inhibiting potassium channels, resulting in the prolongation of the action potential and refractory period.
  2. It is specifically indicated for patients with a history of non-permanent atrial fibrillation or atrial flutter.
  3. Multaq should not be used in patients with severe heart failure or those with permanent atrial fibrillation due to increased risk of adverse effects.
  4. Common side effects include gastrointestinal disturbances, bradycardia, and skin reactions.
  5. Patients on Multaq should avoid grapefruit juice as it can increase the drug's plasma concentration and risk of toxicity.

Review Questions

  • What is the primary mechanism of action for Multaq?
  • In which patients is the use of Multaq contraindicated?
  • What dietary restriction should patients be aware of when taking Multaq?

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