Mirabegron

Definition

Mirabegron is a beta-3 adrenergic agonist used to treat overactive bladder by relaxing the detrusor muscle during the storage phase, increasing bladder capacity. It offers an alternative to antimuscarinics for patients who do not tolerate or respond well to them.

5 Must Know Facts For Your Next Test

1. Mirabegron works by stimulating beta-3 adrenergic receptors in the bladder.
2. It is primarily used for treating symptoms of overactive bladder, such as urgency, frequency, and urge incontinence.
3. Common side effects of Mirabegron include increased blood pressure, urinary tract infections, and headache.
4. Unlike antimuscarinics, Mirabegron does not cause dry mouth or constipation as common side effects.
5. Mirabegron can be used alone or in combination with other medications for optimal management of overactive bladder symptoms.

Review Questions

• What class of drug is Mirabegron and how does it function in treating overactive bladder?
• List two common side effects associated with Mirabegron use.
• Why might a patient be prescribed Mirabegron instead of an antimuscarinic medication?

Related terms

Antimuscarinics:

Medications that block muscarinic receptors to reduce bladder muscle contractions.

Overactive Bladder:

A condition characterized by sudden urges to urinate that are difficult to control.

Beta-3 Adrenergic Receptor: A receptor located in the detrusor muscle of the bladder that regulates relaxation during urine storage.