Antimuscarinics

Definition

Antimuscarinics are a class of drugs that block the muscarinic acetylcholine receptors, reducing involuntary muscle spasms in the bladder and gastrointestinal tract. They are commonly used to treat conditions like overactive bladder and urinary incontinence.

5 Must Know Facts For Your Next Test

1. Antimuscarinics work by inhibiting the parasympathetic nervous system, which controls bladder contractions.
2. Common side effects include dry mouth, constipation, blurred vision, and urinary retention.
3. Examples of antimuscarinic drugs include oxybutynin, tolterodine, and solifenacin.
4. These medications are contraindicated in patients with glaucoma due to the risk of increased intraocular pressure.
5. Antimuscarinics can interact with other medications that also have anticholinergic effects, increasing the risk of adverse reactions.

Review Questions

• What is the primary mechanism of action for antimuscarinic drugs?
• Name three common side effects associated with antimuscarinics.
• Why should antimuscarinics be used cautiously in patients with glaucoma?

Related terms

Urinary Antispasmodics: Medications used to relieve muscle spasms in the urinary tract.

Anticholinergics: A broader class of drugs that block acetylcholine receptors throughout the body.

Overactive Bladder: A condition characterized by sudden urges to urinate and frequent urination.