Meloxicam

Definition

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins.

5 Must Know Facts For Your Next Test

1. Meloxicam primarily targets COX-2 over COX-1, which helps minimize gastrointestinal side effects.
2. It is commonly prescribed for conditions like osteoarthritis and rheumatoid arthritis.
3. Meloxicam can lead to increased risk of cardiovascular events such as heart attack or stroke.
4. It should be used with caution in patients with renal impairment due to potential nephrotoxicity.
5. Common side effects include gastrointestinal upset, headache, and dizziness.

Review Questions

• What enzyme does Meloxicam inhibit to reduce inflammation?
• What are two common conditions for which Meloxicam is prescribed?
• Name one potential serious side effect of Meloxicam.

Related terms

Cyclooxygenase (COX): An enzyme that converts arachidonic acid into prostaglandins, promoting inflammation.

Prostaglandins: Lipid compounds that have diverse hormone-like effects, including promoting inflammation.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs): A class of drugs that reduce pain, decrease fever, prevent blood clots, and in higher doses, decrease inflammation.