Lipitor

Definition

Lipitor is the brand name for atorvastatin, a statin medication used to lower cholesterol levels and reduce the risk of cardiovascular disease. It works by inhibiting HMG-CoA reductase, an enzyme involved in cholesterol production in the liver.

5 Must Know Facts For Your Next Test

1. Lipitor is primarily used to treat high cholesterol and prevent cardiovascular events such as heart attacks and strokes.
2. Common side effects of Lipitor include muscle pain, fatigue, and digestive problems.
3. It is metabolized mainly by the liver enzyme CYP3A4, which can lead to interactions with other medications metabolized by this pathway.
4. Patients on Lipitor should have their liver function monitored regularly due to potential hepatotoxicity.
5. Lifestyle changes such as diet and exercise are recommended in conjunction with Lipitor for optimal lipid-lowering effects.

Review Questions

• What enzyme does Lipitor inhibit to lower cholesterol levels?
• What are common side effects associated with taking Lipitor?
• Why is it important to monitor liver function in patients taking Lipitor?

Related terms

Statins: A class of drugs that lower cholesterol levels by inhibiting HMG-CoA reductase.

HMG-CoA Reductase Inhibitors: Medications that block the action of HMG-CoA reductase, an enzyme involved in cholesterol synthesis.

PCSK9 Inhibitors: A class of drugs that reduce LDL cholesterol levels by enhancing the liver's ability to remove LDL from the blood.