Ibandronate

Definition

Ibandronate is a bisphosphonate medication used to treat and prevent osteoporosis by inhibiting bone resorption. It is commonly administered orally or via injection.

5 Must Know Facts For Your Next Test

1. Ibandronate works by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density.
2. It is typically prescribed for postmenopausal women who are at increased risk of fractures.
3. The oral form of ibandronate should be taken with a full glass of water on an empty stomach to maximize absorption.
4. Patients must remain upright for at least 30 minutes after taking ibandronate to prevent esophageal irritation.
5. Common side effects include gastrointestinal issues, such as dyspepsia and esophagitis.

Review Questions

• What is the mechanism of action of ibandronate in treating osteoporosis?
• Why must patients remain upright after taking oral ibandronate?
• What are common side effects associated with ibandronate use?

Related terms

Bisphosphonates: A class of drugs that prevent the loss of bone density by inhibiting osteoclast activity.

Osteoporosis: A medical condition characterized by weak and brittle bones, increasing the risk of fractures.

Osteoclasts: Cells that break down bone tissue, playing a crucial role in bone resorption and remodeling.