Glucovance

Definition

Glucovance is a combination oral antidiabetic medication that contains glyburide and metformin. It is used to improve blood sugar control in adults with type 2 diabetes.

5 Must Know Facts For Your Next Test

1. Glucovance combines the sulfonylurea glyburide and the biguanide metformin.
2. Glyburide increases insulin secretion from the pancreas, while metformin decreases glucose production by the liver and improves insulin sensitivity.
3. Common side effects include gastrointestinal issues like nausea and diarrhea.
4. Patients need to monitor for signs of lactic acidosis, a rare but serious complication associated with metformin.
5. Glucovance is contraindicated in patients with renal impairment or metabolic acidosis.

Review Questions

• What two active ingredients are found in Glucovance?
• How does Glucovance help control blood sugar levels in type 2 diabetes?
• What are some common side effects of taking Glucovance?

Related terms

Glyburide: A sulfonylurea class drug that stimulates pancreatic beta cells to release insulin.

Metformin: A biguanide class drug that reduces hepatic glucose production and improves insulin sensitivity.

Lactic Acidosis: A rare but serious condition characterized by an accumulation of lactate in the body, which can be a side effect of metformin.