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Furadantin

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Pharmacology for Nurses

Definition

Furadantin is a brand name for nitrofurantoin, an antibiotic used to treat urinary tract infections (UTIs). It works by inhibiting bacterial enzyme systems, interfering with carbohydrate metabolism and cell wall formation.

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5 Must Know Facts For Your Next Test

  1. Furadantin is primarily effective against gram-negative and some gram-positive bacteria in the urinary tract.
  2. It is often prescribed for acute uncomplicated UTIs but not suitable for treating kidney infections or systemic infections.
  3. Common side effects include nausea, headache, and discoloration of urine.
  4. Patients with renal impairment should use Furadantin cautiously as it may accumulate to toxic levels.
  5. It is typically administered in a macrocrystalline form which allows slower absorption and fewer gastrointestinal side effects.

Review Questions

  • What types of bacteria does Furadantin primarily target?
  • Why should Furadantin be used cautiously in patients with renal impairment?
  • What are some common side effects associated with Furadantin?

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