Fragmin

Definition

Fragmin is a brand name for dalteparin, a low molecular weight heparin (LMWH) used to prevent and treat blood clots. It works by inhibiting factor Xa and IIa, reducing the formation of thrombi.

5 Must Know Facts For Your Next Test

1. Fragmin is administered subcutaneously.
2. It is often used for patients undergoing surgery or those with cancer to prevent deep vein thrombosis (DVT).
3. Monitoring of platelet counts is important due to the risk of heparin-induced thrombocytopenia (HIT).
4. Fragmin has a longer half-life than unfractionated heparin, allowing for less frequent dosing.
5. It does not require routine coagulation monitoring like its unfractionated counterpart.

Review Questions

• What are the primary clinical uses of Fragmin?
• Why is it important to monitor platelet counts in patients receiving Fragmin?
• How does the administration route of Fragmin differ from that of oral anticoagulants?

Related terms

Heparin: An anticoagulant that prevents clot formation by inhibiting thrombin and factor Xa.

Warfarin: An oral anticoagulant that inhibits vitamin K-dependent clotting factors.

Thrombocytopenia: A condition characterized by abnormally low levels of platelets in the blood, which can be a side effect of certain anticoagulants like heparin.