Fosfomycin tromethamine

Definition

Fosfomycin tromethamine is an antibiotic used to treat uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria. It works by inhibiting bacterial cell wall synthesis.

5 Must Know Facts For Your Next Test

1. Fosfomycin tromethamine is typically administered as a single oral dose, making it convenient for patients.
2. It is effective against a range of Gram-positive and Gram-negative bacteria, including E. coli, which commonly causes UTIs.
3. The drug is well-tolerated with minimal side effects, the most common being gastrointestinal disturbances.
4. Fosfomycin tromethamine achieves high concentrations in the urine, which enhances its efficacy in treating UTIs.
5. It can be used as an alternative treatment for patients allergic to other antibiotics such as penicillins or sulfonamides.

Review Questions

• What is the primary use of Fosfomycin tromethamine?
• How does Fosfomycin tromethamine inhibit bacterial growth?
• Why might Fosfomycin tromethamine be preferred over other antibiotics for some patients?

Related terms

Nitrofurantoin: An antibiotic commonly used to treat and prevent urinary tract infections.

Trimethoprim/Sulfamethoxazole: A combination antibiotic that treats various types of infections including UTIs.

Ciprofloxacin: A broad-spectrum antibiotic often used to treat serious bacterial infections including complicated UTIs.