Fludarabine
from class: Pharmacology for Nurses Definition Fludarabine is a chemotherapy drug used primarily to treat chronic lymphocytic leukemia (CLL). It interferes with the growth of cancer cells, leading to their destruction.
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Predict what's on your test 5 Must Know Facts For Your Next Test Fludarabine is an antimetabolite that inhibits DNA synthesis. It is administered intravenously. Common side effects include bone marrow suppression, increased risk of infection, and fatigue. Patients taking fludarabine are often monitored for tumor lysis syndrome. Fludarabine can be used in combination with other drugs like cyclophosphamide and rituximab for more effective treatment. Review Questions What type of leukemia is Fludarabine primarily used to treat? How does Fludarabine work at the cellular level? Name two common side effects of Fludarabine.
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