Enoxaparin

Definition

Enoxaparin is a low molecular weight heparin (LMWH) used as an anticoagulant to prevent and treat blood clots. It inhibits factor Xa and IIa, reducing the risk of thrombosis.

5 Must Know Facts For Your Next Test

1. Enoxaparin is administered subcutaneously.
2. It has a longer half-life compared to unfractionated heparin, allowing for less frequent dosing.
3. Common uses include prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE), especially after surgery.
4. Monitoring of anti-Xa levels may be necessary in certain populations, such as patients with renal impairment or pregnant women.
5. Side effects can include bleeding, thrombocytopenia, and injection site reactions.

Review Questions

• What is the primary mechanism of action for Enoxaparin?
• Why might Enoxaparin be preferred over unfractionated heparin in some clinical scenarios?
• What are common side effects associated with Enoxaparin use?

Related terms

Heparin: An anticoagulant that inhibits thrombin and factor Xa, often used intravenously for rapid anticoagulation.

Warfarin: An oral anticoagulant that inhibits vitamin K dependent clotting factors to prevent blood clots.

Thrombocytopenia: A condition characterized by abnormally low levels of platelets in the blood, which can be a side effect of anticoagulants like Enoxaparin.