Eliquis

Definition

Eliquis is an oral anticoagulant that inhibits Factor Xa, reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. It is also used for the prevention and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE).

5 Must Know Facts For Your Next Test

1. Eliquis (apixaban) works by inhibiting Factor Xa, a key enzyme in the coagulation cascade.
2. It is primarily metabolized in the liver and excreted through both renal and fecal pathways.
3. Eliquis has a rapid onset of action, usually within 1-2 hours after oral administration.
4. Unlike warfarin, Eliquis does not require regular blood monitoring for INR levels.
5. Common side effects include bleeding complications such as gastrointestinal bleeding or bruising.

Review Questions

• What is the primary mechanism of action for Eliquis?
• Why does Eliquis not require regular INR monitoring compared to warfarin?
• What are two common indications for prescribing Eliquis?

Related terms

Warfarin: An oral anticoagulant that inhibits vitamin K-dependent clotting factors.

Heparin: An injectable anticoagulant that activates antithrombin III to inhibit thrombin and Factor Xa.

Factor Xa Inhibitors: A class of anticoagulants including drugs like Eliquis that specifically target Factor Xa.