Diltiazem

Definition

Diltiazem is a calcium channel blocker used to treat hypertension, angina, and certain types of arrhythmias. It works by relaxing the muscles of your heart and blood vessels.

5 Must Know Facts For Your Next Test

1. Diltiazem is classified as a Class IV antiarrhythmic drug.
2. It inhibits the influx of calcium ions during membrane depolarization of cardiac and vascular smooth muscles.
3. Common side effects include dizziness, flushing, headache, and edema.
4. Diltiazem can interact with other medications like beta-blockers and digoxin, potentially increasing their effects.
5. It is available in both immediate-release and extended-release formulations.

Review Questions

• What class of antiarrhythmic drugs does diltiazem belong to?
• How does diltiazem affect calcium ion movement in cardiac and vascular tissues?
• Name two common side effects associated with diltiazem.

Related terms

Verapamil: Another Class IV calcium channel blocker used to treat similar conditions as diltiazem.

Amlodipine: A calcium channel blocker primarily used for hypertension and angina but not classified as an antiarrhythmic drug.

Digoxin: A cardiac glycoside that can interact with diltiazem, leading to increased levels and potential toxicity.