Demadex

Definition

Demadex is a brand name for torsemide, a loop diuretic used to treat edema associated with heart failure, renal disease, or liver disease. It is also used for managing hypertension.

5 Must Know Facts For Your Next Test

1. Demadex works by inhibiting the Na+/K+/2Cl- carrier in the thick ascending limb of the loop of Henle.
2. It is more potent and has a longer duration of action compared to furosemide.
3. Common side effects include dehydration, electrolyte imbalances (especially hypokalemia), and hypotension.
4. Demadex can be administered orally or intravenously.
5. Regular monitoring of kidney function and electrolytes is essential during Demadex therapy.

Review Questions

• What mechanism does Demadex use to exert its diuretic effect?
• How does Demadex compare to furosemide in terms of potency and duration?
• What are some common side effects associated with Demadex?

Related terms

Furosemide: A loop diuretic used to treat edema and hypertension.

Hypokalemia: A condition characterized by low levels of potassium in the blood.

Loop of Henle: A section of the nephron in the kidney where loop diuretics like Demadex act.