Dalteparin

Definition

Dalteparin is a low molecular weight heparin (LMWH) used to prevent and treat deep vein thrombosis (DVT) and pulmonary embolism (PE). It acts by inhibiting factor Xa and thrombin, reducing blood clot formation.

5 Must Know Facts For Your Next Test

1. Dalteparin has a longer half-life compared to unfractionated heparin, allowing for once or twice daily dosing.
2. It is administered subcutaneously, not intravenously.
3. Dalteparin requires less frequent monitoring of anticoagulant effect compared to unfractionated heparin.
4. It is often used in patients undergoing surgery or those with cancer to prevent thromboembolic events.
5. Patients on dalteparin should be monitored for signs of bleeding and thrombocytopenia.

Review Questions

• What is the primary mechanism of action of dalteparin?
• How is dalteparin typically administered?
• Why might dalteparin be preferred over unfractionated heparin in certain clinical scenarios?

Related terms

Heparin: An anticoagulant that prevents the formation of blood clots by inhibiting thrombin and factor Xa.

Warfarin: An oral anticoagulant that works by inhibiting vitamin K-dependent clotting factors.

Enoxaparin: Another low molecular weight heparin similar to dalteparin, used for preventing and treating blood clots.