Coumadin

Definition

Coumadin, also known as warfarin, is an oral anticoagulant medication used to prevent the formation of harmful blood clots. It works by inhibiting the synthesis of vitamin K-dependent clotting factors.

5 Must Know Facts For Your Next Test

1. Coumadin is primarily used to prevent thromboembolic events such as stroke, deep vein thrombosis (DVT), and pulmonary embolism (PE).
2. The therapeutic effect of Coumadin is monitored using the International Normalized Ratio (INR), with a typical target range between 2.0 and 3.0.
3. Patients on Coumadin need to maintain a consistent intake of vitamin K in their diet, as fluctuations can affect drug efficacy.
4. Common side effects include bleeding complications, which require immediate medical attention if severe.
5. Drug interactions are significant with Coumadin; many medications, foods, and supplements can either increase or decrease its anticoagulant effect.

Review Questions

• What is the primary use of Coumadin?
• How is the effectiveness of Coumadin therapy monitored?
• Why must patients maintain a consistent intake of vitamin K while taking Coumadin?

Related terms

Warfarin: Another name for Coumadin, an oral anticoagulant that inhibits vitamin K-dependent clotting factors.

Heparin: An injectable anticoagulant that works by activating antithrombin III to inhibit thrombin and factor Xa.

INR (International Normalized Ratio): A standardized measure used to monitor blood coagulation in patients on anticoagulant therapy like warfarin.