Chlordiazepoxide

Definition

Chlordiazepoxide is a benzodiazepine used primarily for the treatment of anxiety disorders and alcohol withdrawal symptoms. It works by enhancing the activity of GABA, a neurotransmitter that inhibits brain activity.

5 Must Know Facts For Your Next Test

1. Chlordiazepoxide is commonly known by the brand name Librium.
2. It is often used in the management of acute alcohol withdrawal to prevent severe symptoms such as seizures.
3. Common side effects include drowsiness, confusion, and ataxia.
4. It has a long half-life, which allows for less frequent dosing compared to other benzodiazepines.
5. Chlordiazepoxide should be used with caution in patients with hepatic impairment due to its metabolism in the liver.

Review Questions

• What are the primary uses of chlordiazepoxide?
• What neurotransmitter's activity is enhanced by chlordiazepoxide?
• Why should chlordiazepoxide be used cautiously in patients with liver impairment?

Related terms

Benzodiazepine: A class of drugs that act as central nervous system depressants, commonly used for treating anxiety and insomnia.

GABA (Gamma-Aminobutyric Acid): A neurotransmitter in the brain that inhibits nerve transmission, leading to calming effects.

Alcohol Withdrawal Syndrome: A set of symptoms that can occur when an individual reduces or stops alcohol consumption after prolonged use.