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Cariprazine

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Pharmacology for Nurses

Definition

Cariprazine is an atypical antipsychotic used primarily to treat schizophrenia and bipolar disorder. It works by modulating dopamine and serotonin receptors in the brain.

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5 Must Know Facts For Your Next Test

  1. Cariprazine has a high affinity for D3 and D2 dopamine receptors, with preference for the D3 subtype.
  2. It is effective in treating both positive and negative symptoms of schizophrenia.
  3. Common side effects include akathisia, insomnia, and gastrointestinal disturbances.
  4. Cariprazine has a long half-life, which might result in delayed onset of therapeutic effects but also allows for less frequent dosing.
  5. It can interact with CYP3A4 inhibitors or inducers, potentially altering its effectiveness or increasing side effects.

Review Questions

  • What are the primary conditions treated with Cariprazine?
  • Which neurotransmitter systems does Cariprazine primarily affect?
  • Name two common side effects associated with Cariprazine.

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